What is recurrent Glioblastoma?
‘Glioblastoma’ is a type of aggressive brain tumour, starting from cells called astrocytes.
The word ‘glioma’ refers to tumours starting in the brain. ‘Glioblastoma’ is a type of aggressive advanced-stage glioma, starting from cells called astrocytes. A Grade IV tumour according to the World Health Organization, it is also often referred to as Glioblastoma multiforme (GBM). It is a rare tumour, with about less than 10 per 100,000 people reported to be affected globally. GBM can be located anywhere in the brain, but, do not regularly spread outside of the brain. GBM accounts for more than 60% of all brain tumours in adults.
When cancer returns after a period of remission, it is called as recurrent cancer. GBM is very likely to recur. Glioblastoma has a less favorable prognosis mainly due to its high chance of tumour recurrence. Research shows that more than 90% of patients with glioma show recurrence and that near the original tumour location. However, it is still difficult to clearly define recurrent GBM with the available knowledge and techniques.
CT/CAT scan: Computed Tomography scan GBM: Glioblastoma multiforme MRI scan: Magnetic resonance imaging scan MRS: Magnetic resonance spectroscopy PET scan: Positron emission tomography scan rGBM: Recurrent glioblastoma multiforme TMZ: temozolomide VEGF: Vascular Endothelial Growth Factor
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